HIGHLIGHTS
- who: Qian Li and collaborators from the Department of Pediatric Surgery, Drvon Hauner Children`s Hospital, University Hospital, LMU Munich, Munich, Germany have published the research work: Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma, in the Journal: Cancers 2022, 4196 of 15/02/2019
- what: The authors focused on the three PDX cell lines HB-214, HB-282, and HB-303, which showed the highest sensitivity to mebendazole, with clinically achievable IC50 values of 1.63 u00b5M, 4.53 u00b5M, and 1.59 u00b5M, respectively. The authors selected this PDX line . . .
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