Targeting the urotensin ii/ut g protein-coupled receptor to counteract angiogenesis and mesenchymal hypoxia/necrosis in glioblastoma

HIGHLIGHTS

  • who: Hélène Castel from the University of Campania Luigi Vanvitelli, Italy have published the research work: Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma, in the Journal: (JOURNAL)
  • what: The authors characterized the expression of UII peptides and their receptor UT in a series of human glioma biopsies compared with normal brain tissue by immunohistochemistry and from transcriptome array analyses of gliomas from To verify a possible autocrine/paracrine mechanism in which UII may in turn induce UTS2 or UTS2R expression encoding UII . . .

     

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