Targeting viral cccdna for cure of chronic hepatitis b

HIGHLIGHTS

  • who: Gaëtan Ligat from the Université de Strasbourg, Strasbourg, France have published the research work: Targeting Viral cccDNA for Cure of Chronic Hepatitis B, in the Journal: (JOURNAL)
  • what: While functional cure characterized by loss of HBsAg is the first goal of novel antiviral therapies curative treatments eliminating cccDNA remain the ultimate goal. While conceptually highly innovative, the approaches described above are largely still at the discovery or preclinical stage of development.
  • future: Studies are needed to understand the role of check point inhibitors in the management of CHB.

SUMMARY . . .

 

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