HIGHLIGHTS
- who: Christopher H. Douse from the University of Cambridge , QH, UK have published the research work: TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors report elsewhere the crystal_structure of a minimal TASOR-Periphilin complex, showing that TASOR(1014-1095) contributes directly to binding the Periphilin C-terminus24. This study provides a molecular characterization of TASOR and how it contributes to HUSH function. The authors report striking homology in the domain organization of the HUSH complex and the yeast RNA . . .
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