Tau exon 10 inclusion by prpc through downregulatinggsk3 activity

HIGHLIGHTS

  • who: Laia Lidón and collaborators from the Department Cell Biology, Physiology and Immunology, University, Spain have published the Article: Tau Exon 10 Inclusion by PrPC through DownregulatingGSK3 Activity, in the Journal: (JOURNAL)
  • what: The authors aimed to analyze the role PrPC and the implication GSK3β in the regulation exon 10 alternative splicing. The authors aimed to analyze GSK3β activity after PrPC ablation in the animal models. Initially the authors aimed to determine whether overexpression of PrPC at initial AD Braak stages (from I to II) might affect not only tau levels but also tau . . .

     

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