Tau seeding activity in various regions of down syndrome brain assessed by two novel assays

HIGHLIGHTS

• who: Nana Jin from the Frozen tissue samples from the TC, FC, OC, CBC, and CC of DS and normal control brains (Table, ) were obtained from the Brain Bank for Developmental Disabilities and Aging of our instituteDiagnosis of DS trisomy , was extracted from subjects` medical records. Selection of control subjects was based on the diagnostic criteria developed at a consensus conference of the National Institute of Aging and the Reagan Institute. Cases with diagnosis of dementia, including AD and Parkinson disease were excluded. Cases with brain tumors, metastases, hemorrhages, multiple small infarcts, and brains with gross traumatic . . .
  

   

  

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