Tdp-43 proteinopathy and tauopathy: do they have pathomechanistic links?

HIGHLIGHTS

• who: Yuichi Riku et al. from the Institute for Medical Science of Aging, Aichi Medical University, Nagakute, Japan have published the Article: TDP-43 Proteinopathy and Tauopathy: Do They Have Pathomechanistic Links?, in the Journal: (JOURNAL)
• what: LATEAutopsy-based (Figure 5).
• future: Another study addressing 10 ALS-TDP patients reported that tau aggregation was observed in the entorhinal cortex of all assayed patients and ALS patients with cognitive impairment showed a broader extension of neuronal and glial tau pathology than those without cognitive impairment .

SUMMARY

Neuronal and glial aggregates . . .

 



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