HIGHLIGHTS
- who: Rodolphe G. Lopez from the (UNIVERSITY) have published the research: TEL Is a Sequence-specific Transcriptional Repressor*, in the Journal: (JOURNAL)
- what: The authors show here that TEL is a sequence-specific transcriptional repressor of ETS-binding_site-driven transcription of model and natural promoters.
- how: To delineate the domain(s) involved in the repressive activity of Gal4-TEL-(120 - 452) the authors analyzed the activity of a series of deletion mutants in its TEL-derived moiety (Fig 6A).
SUMMARY
TEL is unusual among other ETS proteins by its . . .
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