Telomere targeting approaches in cancer: beyond length maintenance

HIGHLIGHTS

  • who: Eleonora Vertecchi and collaborators from the Institute of Molecular Biology and Pathology, National Research Council, Rome, Italy, c/o Department of Biology and Biotechnology, Sapienza University of Rome, Via degli Apuli , have published the research work: Telomere Targeting Approaches in Cancer: Beyond Length Maintenance, in the Journal: (JOURNAL)
  • what: Telomeres are nucleoprotein complexes involved in genome stability, cell proliferation, cancer predisposition and aging.
  • how: Previous results showed that TRF1 inhibition impaired the growth of K-Ras-induced lung cancer in p53-deficient mice without significant side effects .
  • future: According to . . .

     

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