HIGHLIGHTS
- who: August and colleagues from the Catholic University of the Sacred Heart, Italy have published the research: Temozolomide hexadecyl ester targeted plga nanoparticles for drug-resistant glioblastoma therapy via intranasal administration, in the Journal: (JOURNAL)
- what: The authors further constructed TMZ16e-loaded NPs, and chose intranasal administration to deliver TMZ16e to the brain more effectively and focus on glioma sites, aiming to provide a basis for the clinical application of TMZ16e and a potential strategy for the clinical treatment of drug-resistant gliomas.
- how: The authors investigated the anti-drug resistant mechanism by . . .
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