Temozolomide-induced rna interactome uncovers novel lncrna regulatory loops in glioblastoma

HIGHLIGHTS

• who: Sabrina Fritah et al. from the Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA have published the article: Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma, in the Journal: (JOURNAL)
• what: The authors focused on the composition of motifs involving lncRNAs, as such motifs were only present in the most sensitive GSCs (NCH601). The authors report that GSCs elicit a heterogeneous cellular and transcriptional response to acute TMZ exposure. The study provides a comprehensive overview of the RNA regulatory circuits induced by TMZ and lays the basis for . . .
  

   

  

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