Temperature-controlled structural alterations of an rna thermometer*

HIGHLIGHTS

• who: Saheli Chowdhury from the (UNIVERSITY) have published the article: Temperature-controlled Structural Alterations of an RNA Thermometer*, in the Journal: (JOURNAL) of June/27,/2003
• what: The authors show here by a series of in_vivo and in_vitro approaches that ROSE is a sensitive thermometer responding in the physiologically relevant temperature range between 30 and 40 u00b0C. Point mutations predicted to disrupt base_pairing enhanced expression at 30 u00b0C. Compensatory mutations restored repression, emphasizing the importance of secondary_structures in the sensory RNA. This study shows that expression of ROSE-containing heat shock genes is tightly controlled . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.