HIGHLIGHTS
SUMMARY
Proper modification of GG could reduce its gelling temperature to be appropriate for the human body in_vivo, while maintaining its ion-responsive nature. The authors demonstrated the applicability of GSH-GG as a DOX-loading and in situ gelling material in_vitro for selective 4T1 cancer cytotoxicity. The DOX can be readily loaded into the GSH-GG to obtain DOX-loaded GSH-GG by simply using the DOX solution as the solvent. After adding 16 mL of saline, the viscosity of 1.5% DOX-loaded GSH-GG reached 5510 mPa.s, while 0.5% DOX . . .
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