Temporal lobe malformations in achondroplasia: expanding the brain imaging phenotype associated with fgfr3-related skeletal dysplasias

HIGHLIGHTS

  • who: Skeletal Dysplasias and colleagues from the (UNIVERSITY) have published the paper: Temporal Lobe Malformations in Achondroplasia: Expanding the Brain Imaging Phenotype Associated with FGFR3-Related Skeletal Dysplasias, in the Journal: (JOURNAL) of December/31,/2015

SUMMARY

    Common neuroimaging findings were incomplete hippocampal rotation (12 children), oversulcation of the mesial temporal lobe (11 children), loss of gray-white matter differentiation of the mesial temporal lobe (5 children), and a triangular shape of the temporal horn (6 children). Abnormal gyration of the temporal lobes has been described in thanatophoric dysplasia on prenatal sonography13-15 . . .

     

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