Terra g-quadruplex stabilization as a new therapeutic strategy for multiple myeloma

HIGHLIGHTS

• who: Francesca Scionti from the Male , NODSCID mice (6- to, weeks old have published the research: TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma, in the Journal: (JOURNAL)
• what: The authors investigated in vitro and in vivo anti-MM activities of hit 17. The authors focused on the expression level of oncogenes like BCL2, KRAS and MYC. The DNA repair gene signature identified in this study show a correlation with MM outcome. The authors provide evidence of anti-MM activity of hit 17 in_vitro and in_vivo models.
• how: To . . .
  

   

  

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