Tert and tet2 genetic variants affect leukocyte telomere length and clinical outcome in coronary artery disease patients—a possible link to clonal hematopoiesis

HIGHLIGHTS

• who: Trine B. Opstad and collaborators from the Center for Clinical Heart Research, Department of Cardiology, University Hospital Ullevål have published the Article: TERT and TET2 Genetic Variants Affect Leukocyte Telomere Length and Clinical Outcome in Coronary Artery Disease Patients—A Possible Link to Clonal Hematopoiesis, in the Journal: Biomedicines 2022, 10, 2027. of 19/08/2022
• what: The authors aimed to investigate two genetic variants, reported as germline mutations , that could potentially induce somatic mutations in HSCs ensuing CHIP development: the TERT intron 5 rs7705526 variant and the TET2p.Ile1762Val rs2454206 missense mutation . . .
  

   

  

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