HIGHLIGHTS
- who: Anja Toliu0107 from the (UNIVERSITY) have published the research work: TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation, in the Journal: (JOURNAL)
- what: In the recent study the authors have observed a negative influence of PARP-1 on local TET-mediated of a single gene and in this study the authors further explore interplay. Expanding on the previous work the authors show that both and can be in vitro PARylated by PARP-1 and PARP-2 enzymes and that negatively affects the catalytic activity in vitro. The authors show that . . .
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