Tet proteins regulate t cell and inkt cell lineage specification in a tet2 catalytic dependent manner

HIGHLIGHTS

  • who: Tarmo Ä from the Sciences Research Center, Greece University of Michigan, United States have published the research: TET proteins regulate T cell and iNKT cell lineage specification in a TET2 catalytic dependent manner, in the Journal: (JOURNAL)
  • what: The authors seek to understand how TET proteins, and in particular TET2 and TET3, which are most highly expressed in T_cells , impact the gene_expression program of CD4 SP cells. The analysis demonstrated a similar gain of cytosine methylation in Tet2/3 DKO iNKT_cells . The analysis demonstrated that Th-POK expression, evaluated by median fluorescence intensity, was . . .

     

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