HIGHLIGHTS
- who: Miryam Müller et al. from the Institute of Biochemistry, Medical Faculty, Christian-Albrechts-University Kiel, Kiel, Germany have published the paper: Tetraspanin 8 Subfamily Members Regulate Substrate-Specificity of a Disintegrin and Metalloprotease, in the Journal: Cells 2022, 2683 of 16/02/2016
- what: The authors show that Tspan8 use different strategies to ADAM17 substrate selectivity. The authors demonstrate that in particular Tspan8 associates with both ADAM17 and α and promotes ADAM17-mediated α release through recruitment of ADAM17 into Tspan-enriched micro-domains. The authors focused the analysis on the members Tspan8, CD9 and . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.