Tfap2c-mediated upregulation of tgfbr1 promotes lung tumorigenesis and epithelial–mesenchymal transition

HIGHLIGHTS

• who: Wanyeon Kim from the Tumor xenografts in nude mice The effects of TFAP C and , on tumor development were analyzed using a xenograft mouse model as described previously [25]Six-week-old male BALB/c athymic nude mice (Central Lab Animals, Seoul, South Korea) were used for the in vivo experiments. The animal protocols were approved by the Institutional Animal Care and Use Committee of Pusan National University (Busan, South Korea), and performed in accordance with the provisions of the NIH Guide for the Care and Use of Laboratory Animals. Mice were housed individually or in . . .
  

   

  

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