Tgf-#_#x03b2; inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic chagas#_#x2019; heart disease

HIGHLIGHTS

  • who: Roberto Rodrigues Ferreira and collaborators from the Universidade Federal Minas Gerais, Grenoble, France have published the paper: TGF-#_#x03B2; inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas#_#x2019; heart disease, in the Journal: (JOURNAL) of July/31,/2019
  • what: The aim of this study was to investigate the effect of GW788388 a selective of TβR1/ALK5 on cardiac function in an experimental model of chronic Chagas' heart disease. This study showed a reduction of parasite load in serum but a lack of clinical . . .

     

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