HIGHLIGHTS
- who: Meena U. Rajagopal and collaborators from the Department of Oncology, Georgetown University Medical Center, Washington, DC, USA have published the article: TGF Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGF Induced EMT in PDAC, in the Journal: (JOURNAL)
- what: The main focus of the study was to delineate metabolic dysregulations accompanying EMT induced by TGFu03b2 treatment in PANC-1 cells.
- future: Tumor cells have been reported to upregulate the expression of ECM proteins including FN1 to create a pro-tumor stromal environment however further investigations are needed to delineate . . .
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