HIGHLIGHTS
- What: The preliminary data from this study show that candidate functional variants were associated with the expression of critical regulators within the JAK-STAT pathway and IFN-stimulated genes, which appear to usually act in a cell type-specific manner . In the latter case, an analysis focusing on the composition of haplotypes instead of individual variants will be a better model for the risk architecture in this region. The major themes and pathways implicated in this analysis show much involvement, no surprise, of the immune system, both adaptive and innate.
- Who: Viktoryia Laurynenka and John . . .
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