The actin bundling activity of itpka mainly accounts for its migration-promoting effect in lung cancer cells

HIGHLIGHTS

• who: Bioscience Reports ( et al. from the University Medical Center Hamburg-Eppendorf, Martinistrasse, Hamburg, Germany have published the paper: The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells, in the Journal: (JOURNAL) of 09/02/2023
• what: The authors demonstrate that under basal conditions the actin bundling activity controls ITPKA-facilitated migration and invasion and in presence of ATP the Ins(1 5)P3 -kinase activity slightly enhances this effect. The authors analyzed this issue in detail by assessing migration and invasion, two essential steps in the . . .
  

   

  

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