The alternative trkaiii splice variant, a targetable oncogenic participant in human cutaneous malignant melanoma

HIGHLIGHTS

• who: Lucia Cappabianca et al. from the Department of Biotechnological and Applied Clinical Sciences, University of L`Aquila, L`Aquila, Italy have published the research: The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma, in the Journal: Cells 2023, 237 of /2023/
• what: In thisbyfirst of alternative TrkAand mRNA_splicing in CMMs and TrkA splice variant behaviour in BRAF(V600E)-mutated A375 melanoma cells, the authors demonstrate a The authors report that TrkAIII expression was frequently and intracellular TrkA isoform immunoreactivity, andmore phosphorylated detected in metastatic BRAF wild-type BRAF-mutated . . .
  

   

  

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