The anaphase-promoting complex/cyclosome: a new promising target in diffuse large b-cell lymphoma and mantle cell lymphoma

HIGHLIGHTS

  • who: Anke Maes from the DepartmentGhent University Amsterdam, Amsterdam, the Netherlands have published the paper: The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma, in the Journal: (JOURNAL) of 16/04/2019
  • what: The aim of this study is to investigate the expression of the APC/C co-activators Cdc20 and Cdh1 and the therapeutic potential of APC/C targeting in DLBCL and MCL. In this study, the mitotic exit regulator APC/ C is identified as a novel, promising target in ABC-DLBCL, GCB-DLBCL . . .

     

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