HIGHLIGHTS
SUMMARY
The gut microbiota, a very complex community of commensal microorganisms including bacteria, Archaea, fungi, protists, and viruses, has emerged as a critical player in the modulation of cancer development. Indeed, the commensal microbiota induces immunological and cellular pathways to prevent cancer and activates inflammasomes, which preserve the host`s cellular and gut integrity. Accordingly, the amelioration of microbiota through the intake of probiotics is recognized as a chemopreventive intervention favoring improvement of the intestinal barrier, bacterial translocation, and maintenance of gut microbiota homeostasis and composition; healthy microbiota also exhibits detoxifying activity against chemical genotoxic . . .
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