The anti-cancer activity of pentamidine and its derivatives (wlc-4059) is through blocking the interaction between s100a1 and rage v domain

HIGHLIGHTS

• who: Nuzhat Parveen and colleagues from the Chemistry Department, National Tsing Hua University, Hsinchu, Taiwan have published the paper: The Anti-Cancer Activity of Pentamidine and Its Derivatives (WLC-4059) Is through Blocking the Interaction between S100A1 and RAGE V Domain, in the Journal: Biomolecules 2023, 13, x FOR PEER REVIEW of 14 pentamidine derivative (WLC-4059) comparing to pentamidine, particularly when the11dose of /2023/
• what: Cell decreased by 1.21-fold. pentamidine was added to. This study has been able to demonstrate that in_vitro, the S100A1 protein interacts directly with the RAGE V domain . . .
  

   

  

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