The antibody landscapes following as03 and mf59 adjuvanted h5n1 vaccination

HIGHLIGHTS

  • who: Johannes B. Goll from the (UNIVERSITY) have published the Article: The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination, in the Journal: (JOURNAL)
  • how: The results showed that these full-length stabilized trimeric HA0 molecules detected more antibodies than monomeric HA0 (Supplementary Fig 1).

SUMMARY

    Influenza HA is a major target for humoral immune_responses, with antibodies directed towards the antigenically variable head domain (HA1) and the highly conserved HA stalk domain (HA2)12,13. There is growing interest in identifying adjuvants that are capable of inducing such broadly reactive . . .

     

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