The antifungal itraconazole is a potent inhibitor of chikungunya virus replication

HIGHLIGHTS

  • who: Lucca R. Policastro et al. from the Su00e3o Carlos Institute of Physics, University of Su00e3o Paulo, Su00e3o Carlos, Brazil have published the article: The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication, in the Journal: Viruses 2022, 14, 1351. of /2022/
  • what: The authors describe the development of a stable CHIKV replicon cell line, the BHK-21-T7-Gluc-nSP-CHIKV-99650, which harbors a replicative replicon expressing Gaussia luciferase (GLuc) as a reporter gene. The authors successfully constructed a replicative CHIKV reporter replicon using homologous recombination in threat yeast, ato strategy . . .

     

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