The antitumor activity of human vγ9vδ2 t cells is impaired by tgf-β through significant phenotype, transcriptomic and metabolic changes

HIGHLIGHTS

• who: Chirine Rafia et al. from the University of Texas MD Anderson Cancer Center, United States have published the article: The antitumor activity of human Vu03b39Vu03b42 T cells is impaired by TGF-u03b2 through significant phenotype, transcriptomic and metabolic changes, in the Journal: (JOURNAL)
• how: DGE-sequencing was performed by the BIRD core facility (SFR Bonamy Nantes University) data were analyzed using R programming tools. Two-way ANOVA and Mann and amp Whitney tests were calculated to assess or not for significant differences. The authors showed that TGF-b exposure severely impacts the cytolytic activity . . .
  

   

  

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