The application of the neuroprotective and potential antioxidant effect of ergotamine mediated by targeting n-methyl-d-aspartate receptors

HIGHLIGHTS

• who: Shinhui Lee et al. from the Department of Biotechnology, Chonnam National University, Gwangju, KoreaGoPath Laboratories, Buffalo Grove, IL, USA have published the research: The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors, in the Journal: Antioxidants 2022, 1471 of /2022/
• what: In this study, ergotamine was identified as a subtype-selective antagonist or modulator that could suppress glutamate-evoked current on these four target subunits of NMDARs.
• how: To in compare resultsmutation with mutant-type the inhibition seems to exert effects on . . .
  

   

  

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