The assessment of 5-aminolevulinic acid photodynamic therapy in glioblastomas

HIGHLIGHTS

  • What: The review discusses ongoing clinical trials, providing insights into optimizing PDT as a transformative treatment for glioblastoma multiforme (GBM) . This approach has the potential to enhance the selectivity and efficacy of PDT for treating brain tumors . This study assessed the impact of NO from glioblastoma cells on ALA-PDT. This study demonstrated that ALA-PDT leads to PpIX accumulation, followed by mitochondrial dysfunction, marked by a decrease in mitochondrial membrane potential and the release of cytochrome c.
  • Who: David Aebisher from the Physical, Medical College of The Rzeszów University, Medical College of The . . .

     

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