HIGHLIGHTS
- What: The authors aimed to i) identify the independent causal relationship between HCC, HCNC and preterm birth risk and ii), investigate the cumulative effect of HCC and HCNC at different pregnancy time points on preterm birth risk in a large sample of an understudied population. The results of the study provide new insights into the causal effect of temporal chronic corticosteroid levels on preterm birth risk, implicating that the corticosteroid level an individual has in first trimester may significantly shape the pregnancy course and its outcomes. The study scope was limited to corticosteroid assessments to pre-pregnancy . . .

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