The axl-pyk2-pkcα axis as a nexus of stemness circuits in tnbc

HIGHLIGHTS

• who: Lohit Khera and colleagues from the Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel Aix Marseille University, Le Centre National de la Recherche Scientifique (CNRS), Developmental Biology Institute of Marseille (IBDM) Unité Mixte de Recherche (UMR), Marseille, France have published the paper: The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC, in the Journal: (JOURNAL)
• what: The authors show that PYK2 depletion and/or inhibition of its kinase activity markedly reduced the steady-state levels of AXL receptor, PKCα and FRA1 TF in various mesenchymal/mesenchymal stem-like . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.