The balance between hydrophobicity/aromaticity and positively charged residues may influence the cell penetration ability

HIGHLIGHTS

  • who: Du00f3ra Soltu00e9sz and collaborators from the Department of Organic Chemistry, Eu00f6tvu00f6s LUniversity, Budapest, Hungary have published the paper: The Balance between Hydrophobicity/Aromaticity and Positively Charged Residues May Influence the Cell Penetration Ability, in the Journal: Pharmaceutics 2023, 15, 1267. of /2023/
  • what: The authors synthesized oligoarginines with AMBA, Dabcyl and Dabcyl-AMBA modifications at their N-terminus and examined their cellular uptake on EBC-1 cells.
  • how: The data were analyzed with FACSDiva 5.0 software (BD Bioscience San Jose CA USA). The earlier results showed that both the Dabcyl and . . .

     

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