The bio-diversity and the role of gut microbiota in postmenopausal women with luminal breast cancer treated with aromatase inhibitors: an observational cohort study

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SUMMARY

    In postmenopausal women, the adipose_tissue is able to product estrogen by the aromatization of androgen precursors. Abundant TILs are associated with better outcome for patients with triple negative BC and HER2-positive BC, while the prognostic significance of TILs in estrogen receptor (ER)-positive/HER2-negative BC remains unclear. Secondary outcomes were to compare TILs levels and serum marker of immune-activation, immune-exhaustion and bacterial translocation among cases and controls. Considering statistically significant difference (p=0.04) in IL-17 levels among the groups, with pa PGE and CD14, the authors did obtain . . .

     

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