HIGHLIGHTS
- who: Migraine and colleagues from the (UNIVERSITY) have published the article: The calcitonin gene-related peptide receptor antagonist MK-8825 decreases spinal trigeminal activity during nitroglycerin infusion, in the Journal: (JOURNAL)
- what: The authors have used MK-8825, a new potent inhibitor for rat CGRP receptors, which showed concentration-dependent inhibition of capsaicin-evoked dermal blood flow with an EC50 of about 7.4 μM . The aim of this study was to examine if inhibition of CGRP receptors with the new CGRP receptor antagonist MK-8825 is also able to prevent an increase in neuronal . . .
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