The cancer-associated k351n mutation affects the ubiquitination and the translocation to mitochondria of p53 protein*

HIGHLIGHTS

  • who: Michela Muscolini from the (UNIVERSITY) have published the paper: The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein*, in the Journal: (JOURNAL) of November/18,/2011
  • how: Yeast Plasmids Strains and Growth Conditions-In this study the authors used the Saccharomyces cerevisiae strain BY4741 (MAT u2423 his3u232c1 leu2u232c0 met15u232c 0 ura3u232c0) for heterologous expression of native or mutant p53 and the yeast strain W301-1B (MATu2423 ade2-1 ura3-1 his3-1115 leu2-3112 trp1-1 can1-100) transformed with the yeast multicopy YepDP1- 8 vector expressing . . .

     

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