The cancermuts software package for the prioritization of missense cancer variants: a case study of ambra1 in melanoma

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  • who: Matteo Tiberti from the Images were captured with a ChemiDocu2122 MP System (Bio-Rad Laboratories have published the research work: The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma, in the Journal: (JOURNAL) of 25/05/2022
  • what: To validate Cancermuts in a cancer study, the authors focused on the tumor suppressor gene AMBRA1 (autophagy and beclin 1 regulator 1). Visual inspection of the model showed a major structural feature for this model-a u03b2-propeller folded domain spanning regions ~41-203 and ~857-1040 . . .

     

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