The cannabinoid receptor 1 reverse agonist am251 ameliorates radiation-induced cognitive decrements

HIGHLIGHTS

  • who: Vipan K. Parihar and Charles L. Limoli from the Department of Radiation Oncology, University of California, Irvine, Irvine, CA, United States have published the research work: The Cannabinoid Receptor 1 Reverse Agonist AM251 Ameliorates Radiation-Induced Cognitive Decrements, in the Journal: (JOURNAL)
  • what: This study provides novel evidence that AM251 provides wide-ranging benefits to the irradiated CNS. The authors investigated the protective effects of AM251 on select cognitive, cellular, and molecular endpoints impacted by cranial irradiation.
  • how: 2 days after the last injection of AM251 (13 weeks after irradiation) animals in . . .

     

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