The carboxyl-terminal tsp1-homology domain is the biologically active effector peptide of matricellular protein ccn5 that counteracts profibrotic ccn2

HIGHLIGHTS

  • who: Sima Zolfaghari from the Institute for Surgical Research, Oslo University Hospital, Oslo, Norway have published the Article: The carboxyl-terminal TSP1-homology domain is the biologically active effector peptide of matricellular protein CCN5 that counteracts profibrotic CCN2, in the Journal: (JOURNAL)
  • what: The aims of this study was to resolve to what extent the carboxyl-terminal TSP1 domain of CCN5 is a biologically active entity sufficient in conveying the signaling and biological actions of CCN5. Since CCN2 has previously been documented to be essential to the function of fibroblasts , 3 the authors focused on . . .

     

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