HIGHLIGHTS
- who: Marton Fogarasi and Simona Dima from the Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge , RE, UK have published the Article: The Catalytic Domain Mediates Homomultimerization of MT1-MMP and the Prodomain Interferes with MT1-MMP Oligomeric Complex Assembly, in the Journal: Biomolecules 2022, x of 19/08/2022
- what: The authors show that whole ectodomain of can form dimers and higher-order complexes. enzyme is secreted in its active form and multimeric is mediated by Blocking prodomain removal determines enzyme to adopt monomeric structure suggesting that prodomain prevents oligomerization process. binding . . .
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