The catalytic subunit of schizosaccharomyces pombe ck2 (cka1) negatively regulates rna polymerase ii transcription through phosphorylation of positive cofactor 4 (pc4)

HIGHLIGHTS

• who: Diego A. Rojas and colleagues from the Instituto de Ciencias Biomédicas (ICB), Facultad de Ciencias de la Salud, Universidad Autónoma de have published the paper: The Catalytic Subunit of Schizosaccharomyces pombe CK2 (Cka1) Negatively Regulates RNA Polymerase II Transcription through Phosphorylation of Positive Cofactor 4 (PC4), in the Journal: (JOURNAL)
• what: The authors focused the analysis on CK2 phosphorylation sites, and it was found that Ser96, Ser98 and Ser100 are predicted to be phosphorylated by CK2. This work provides an example of the negative regulation of transcriptional cofactor activity by CK2 phosphorylation . . .
  

   

  

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