The cell cycle inhibitor rb is diluted in g1 and contributes to controlling cell size in the mouse liver

HIGHLIGHTS

• who: August et al. from the University of Arizona, United States have published the Article: The cell cycle inhibitor RB is diluted in G1 and contributes to controlling cell size in the mouse liver, in the Journal: (JOURNAL)
• what: The authors aimed to test the in_vivo relevance of a cell size control model, namely, the RB-dilution model, in the liver of genetically engineered mice.
• how: To test for the effect of Cdk4/6 activity on hepatocyte cell size the authors used Palbociclib to inhibit Cdk4/6 activity during liver regeneration following a . . .
  

   

  

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