The cellular prion protein—rock connection: contribution to neuronal homeostasis and neurodegenerative diseases

HIGHLIGHTS

  • who: Benoit Schneider from the UMR, Hôpital Lariboisière, Paris, France, Pharma Research Department, Hoffmann-La-Roche Ltd, Basel, Switzerland East Carolina University, United States have published the research work: The Cellular Prion Protein—ROCK Connection: Contribution to Neuronal Homeostasis and Neurodegenerative Diseases, in the Journal: (JOURNAL)
  • what: Although cellular prion protein PrPC has been known for several decades for its pathological implication in prion diseases, the functions exerted by PrPC remain an enigma.
  • future: Future studies are needed to address whether the hijacking of the PrPC -RhoA-ROCK pathway is a . . .

     

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