The circadian clock protein rev-erbα provides neuroprotection and attenuates neuroinflammation against parkinson’s disease via the microglial nlrp3 inflammasome

HIGHLIGHTS

• who: Liang Kou from the Huazhong University of Science and Technology, Wuhan, China have published the article: The circadian clock protein Rev-erbu03b1 provides neuroprotection and attenuates neuroinflammation against Parkinsonu2019s disease via the microglial NLRP3 inflammasome, in the Journal: (JOURNAL)
• what: The authors explored potential link between core molecule Rev-erbu03b1 and microglia-mediated NLR family pyrin domain-containing 3 (NLRP3) inflammasome in PD pathogenesis. The authors showed for the first time that the normal daily fluctuations of Rev-erbu03b1 were absent in subacute MPTP-induced PD model. Microgliamediated neuroinflammation in PD has been the . . .
  

   

  

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