The classical pathway triggers pathogenic complement activation in membranous nephropathy

HIGHLIGHTS

• who: Larissa Seifert from the Patient samples The study of diagnostic human biopsies was conducted in accordance with federal state and institutional guidelines and approved by the local ethics committee of the Chamber of Physicians in Hamburg (registration number PV5541)Biopsy samples derived from the archive of the Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, and were collected between , and, . Samples were included based on the histological diagnosis of MN, positive immunohistochemical antigen status for PLA , or THSD, and availability of sufficient biopsy material to perform the analyses for this study. No specific exclusion . . .
  

   

  

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