HIGHLIGHTS
- who: Annerose E. Ziegler and colleagues from the Sapienza University of Rome, Italy have published the paper: The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells, in the Journal: (JOURNAL)
- what: The authors performed a detailed characterization of CD56bright NK cells derived from matched peripheral blood and liver tissues on the transcriptional level and by assessing protein expression profiles, and determined their functional activity. The authors report transcriptional, functional, and phenotypical differences between CD56bright ihNK cells and CD56bright pbNK cells.
SUMMARY
While . . .
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