The combination of gefitinib with atra and ato induces myeloid differentiation in acute promyelocytic leukemia resistant cells

HIGHLIGHTS

  • who: Luciana Yamamoto de Almeida from the University of Hong Kong, Hong Kong, SAR China have published the Article: The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells, in the Journal: (JOURNAL)
  • what: The authors demonstrate for the September 2021 | Volume 11 | Article 686445 Gefitinib Sensitizes APL-Resistant Cells to ATRA/ATO first time that this combination was effective for ATRA- and ATO-resistant APL cells, most likely due to an off-target effect. In the present work, the combination of gefitinib and ATRA extended survival in . . .

     

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